CAS No.: | 80-08-0 |
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Formula: | C12h12n2o2s |
EINECS: | 201-248-4 |
Classification: | Organic Analytical Reagents |
Grade: | AR |
Specific Usage: | For Biological Purpose |
Customization: |
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Common Name | 4,4'-Diaminodiphenylsulfone | ||
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CAS Number | 80-08-0 | Molecular Weight | 248.301 |
Density | 1.4±0.1 g/cm3 | Boiling Point | 511.7±35.0 °C at 760 mmHg |
Molecular Formula | C12H12N2O2S | Melting Point | 175-177 °C(lit.) |
MSDS | ChineseUSA | Flash Point | 263.2±25.9 °C |
Symbol | GHS07 |
Signal Word | Warning |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 511.7±35.0 °C at 760 mmHg |
Melting Point | 175-177 °C(lit.) |
Molecular Formula | C12H12N2O2S |
Molecular Weight | 248.301 |
Flash Point | 263.2±25.9 °C |
Exact Mass | 248.061951 |
PSA | 94.56000 |
LogP | 0.94 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.662 |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
Water Solubility | <0.1 g/100 mL at 20 ºC |
4,4'-Diaminodiphenylsulfone (commonly known as DDS or Dapson) is an organic compound with the chemical formula C12H12N2O2S.
Medical Uses: DDS has been primarily used in the treatment of leprosy (Hansen's disease). It is a key component of multidrug therapy regimens for leprosy treatment recommended by the World Health Organization (WHO). DDS helps to kill the bacteria responsible for leprosy and helps control the symptoms of the disease.
Dermatological Conditions: DDS has also been used in the treatment of other dermatological conditions, such as dermatitis herpetiformis, a chronic blistering skin disorder associated with gluten intolerance. It may also be prescribed for certain types of acne or cutaneous vasculitis.
Mechanism of Action: DDS exhibits its antimicrobial effects by inhibiting the production of folic acid in bacteria, thereby interfering with their ability to proliferate and survive. It is believed to act by competitively inhibiting the enzyme dihydropteroate synthase, which is involved in the synthesis of folic acid.
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